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December 18th, 2017
Woman in Pain at Right Deltoid Muscle Lake Forest CA

Aprospective cohort study indicates that platelet-rich plasma (PRP) injection may be a safe and cost-effective treatment alternative for rotator cuff tendinopathy (RCT) without a full-thickness tear of the rotator cuff. The results are presented in Scientific Poster P318, “Platelet Rich Plasma Injection as an Alternative Treatment for Rotator Cuff Tendinitis of Shoulder,” selected as the 2013 Best Poster in the Shoulder and Elbow category, on display in Academy Hall B.

In recent years, PRP has emerged as an effective treatment option for various tendinopathies throughout the body, including the rotator cuff tendon. Turlough O’Donnell, MD, and his colleague Aamir H. Shaikh, MSc, MRCSEd, MCh, of UPMC Beacon Hospital in Dublin, Ireland, sought to evaluate the therapeutic effects of multiple PRP injections administered directly into the supraspinatus tendon, compared with use of corticosteroid injections, in the treatment of RCT.

They prospectively identified 204 patients with poor shoulder function based on Constant-Murley (CMS) shoulder scores and shoulder pain that restricted range of motion (ROM). Only patients with full passive ROM and MRI–confirmed Goutallier grade 2 or less fatty infiltration were included.

Patients were divided into two age- and sex-matched cohorts. The PRP group (n = 102) was treated with PRP injections administered directly into the suprasimatos tendon; the control group (n =102) was treated with 20 mL solution of 0.05 percent bupivacaine and 80 mgs of methylprednisolone into the subacromial space.

Visual analog scale (VAS) pain scores, ROM, and Constant shoulder scores were obtained in all patients 3 months after final injection.

PRP found safe, effective

At 3 months post-injection, the researchers found clinically and statistically significant improvement in VAS pain scores, ROM, and mean Constant scores in both cohorts compared with pre-injection scores (P < 0.001). Although patients in the control group initially had a higher mean CMS score (49.68 vs 48.86), and patients in both groups showed significant improvement after receiving the injections (60.99 vs 80.43), the degree of change in the PRP group was significantly better than in the control group (P = 0.05).

Patients in the PRP group also had significantly better active forward flexion, abduction, and internal rotation at final follow-up than did those in the control group. The mean difference in Constant scores post-injection in the two groups was 19.4. According to the researchers, when this change of estimated means was plotted against pre-injection scores using analysis of variance, the increase in scores was clearly greater in the PRP group than in the steroid group (67.7 percent and 24.9 percent, respectively). In addition, at 1-year follow-up, only 3 patients in the PRP group had undergone surgery for recalcitrant pain, whereas 48 patients in the corticosteroid group had required surgical intervention.

“At 12-month follow-up, patients who received a series of PRP injections were 16 times less likely to have undergone surgical intervention than patients who received corticosteroid injections,” the authors said. The authors concluded that PRP injections are a clinically safe and cost-effective treatment alternative to corticosteroid injections for RCT pain.

To view this as an iPoster, visit http://aaos.posterview.com/
Disclosures: The authors report no conflicts.

By: Maureen Leahy

Posted on behalf of Advanced Healing Institute

22972 El Toro Road
Lake Forest, CA, 92630

Phone: (949) 239-3206

Our Patient Reviews

Advanced Healing Institute

5 / 5.0

Based on 39 reviews

Rich G.

Dr. Reza is a genius. My knee has been bothering me for YEARS since I tore my meniscus playing football. Achy, bothersome, with occasionally a limp. I went in to to get PRP (Platelet Rich Plasma) and it was everything I thought it would be and then some. The whole procedure took less than an hour, very little to no pain and in less than 24 hours my knee felt brand new. If you are looking for a quality Doctor who offers PRP -- go here! The rates are very on point. He is literally THOUSANDS of dollars less than some other clinics and believe me he does such an amazing job, he could charge 10x's and it would still be worth it. Don't sit there suffering, get up and get help. I am actually thinking of getting my other knee done and its not really necessary. Lol.. 10 STARS...

E Y.

Dr Reza is FANTASTIC. Staff is friendly and very accommodating. I was in such pain. He diagnosed the issue (Bursitis) and clearly understood everything about it from A-Z. So efficient and understanding, not to mention making the procedure painless. I barely slept a hour the night before, saw Dr. Reza at 5pm and was feeling a million times better by 7pm. It's been 36 hours and I went from practically a frozen shoulder in pulsating pain to gaining back 70% of my movement range and most importantly "NO PAIN". just stiffness which is the normal symptoms as kindly explained to me by Dr. Reza. Everything is as promised, I am fully confident that I will be back to 100% range of motion within 3 days. I'm still gonna take it easy and slowly stretch my shoulder back to full strength. Without his service, I would probably be feeling like I was hit by a truck laying in bed miserable. Thank you very much Dr. Reza for helping my aging old bones. Cheers!

Geri C.

I can’t say enough about how intelligent Dr. Reza Dehdari is! I came to him to read my MRI for my ankle and he found a tear that multiple Doctors missed!!!! Simply incredible and I trust him throughly. Thank you so much!

Marina S.

Had the PRP procedure and I have to say no pain at all, going on 6 weeks, if you decide to have the PRP listen to Dr. Dehdari's instructions thoroughly and do the physical therapy, it works and I am so pleased and it's getting better and better as days go on, Dr. Reza Dehdari is the best and very emphatic in explaining all your questions soothing away your doubts, and he checks up on you to make sure all is well, after the PRP procedure. Very trustworthy PRP procedure and his assistant Sandy is also the sweetest caring person you will ever meet. I'm a satisfied customer and patient.

Micheal W.

Dr. Reza Dehdari you are an amazing person. Thank you for going the extra mile on my shoulder after three Doctors told me I needed surgery. You took your time and explained everything about what to expect and to be patient while I heal. And that’s exactly what I did was heal, I can’t thank you enough for what you did for me.

Helena L.

Within the last 6 months I've suffered two minor injuries on the same knee which have restricted my mobility and caused me a lot of pain. I've seen an orthopedic dr.,, a pain management dr., and a sports medicine dr., all of which simply told me either surgery or learn to live with the pain! I've heard about PRP as an alternative with a high percentage of success. Thus, I made an appointment to see Dr. Dehdari, and was pleasantly surprised by his high level of knowledge, professionalism and thoroughness. Dr. Dehdari reviewed my MRI (previously ordered by the Orthopedist) explained the extent of my injuries, took X-Rays and an ultrasound to carefully determined if I was a good candidate for PRP. I can only say that I wish more doctors will give you the time, attention and care that Dr. Dehdari provides. Thank you Dr Dehdari, thank you for such high work ethics and patient care. Many thanks to his staff as they are as attentive and caring as Dr. Dehdari. It has been only 24 hrs since I received my PRP treatment and my pain levels have drastically gone down! I highly recommend Dr. Dehdari.

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